Aspects of this topic are discussed in the following places at Britannica.
Because brain alcohol concentrations are difficult to measure directly, the effects of alcohol on the brain are calculated indirectly by noting the physical and mental impairments that typically arise at various levels of blood alcohol concentration, or BAC.
...than 40 percent of fatal crashes in the United States in the 1980s—and pressure from interest groups (e.g., Mothers Against Drunk Driving), many states in the 1990s lowered the legal limit of blood alcohol content (BAC) for drivers from 0.10 mg of alcohol per 100 ml of blood to 0.08 and increased the penalties for driving under the influence.
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