fibrin-stabilizing factor XIIIbiochemistry

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  • effect on drug action ( in drug: Drugs affecting blood )

    ...the conversion of the soluble fibrinogen to soluble fibrin under the influence of the enzyme thrombin (factor IIa). Soluble fibrin is converted to insoluble fibrin strands by activated factor XIII (fibrin-stabilizing factor), and covalent cross-linkages form between the fibrin strands to give a strong and rigid network. Several of the clotting factors (II, VII, IX, X) require the presence of...

  • formation of fibrin ( in fibrin )

    ...entangle platelets, building up a spongy mass that gradually hardens and contracts to form the blood clot. This hardening process is stabilized by a substance known as fibrin-stabilizing factor, or factor XIII.

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fibrin-stabilizing factor XIII. (2009). In Encyclopædia Britannica. Retrieved January 08, 2009, from Encyclopædia Britannica Online: http://www.britannica.com/EBchecked/topic/205883/fibrin-stabilizing-factor-XIII

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