Aspects of this topic are discussed in the following places at Britannica.
...covers an area of 425 square km (164 square miles). The channel through the lake varies in depth from 14 to 26 metres (46 to 85 feet) and extends for about 37 km (23 miles) to Gamboa. At Gamboa, Gaillard (Culebra) Cut through the Continental Divide begins. The channel through the cut has an average depth of about 13 metres (43 feet) and extends some 13 km (8 miles) to the Pedro Miguel Locks....
in canals and inland waterways: The Panama Canal )...above sea level to the Gatun Lake through the Gatun Locks and is retained at the north by these locks and dam and at the south by the Pedro Miguel Locks and Dam. The waterway then runs through the Gaillard Cut, which channels it through the Continental Divide, then between the Pedro Miguel Locks and the Miraflores Lake at an elevation of 54 feet, ships to the Pacific Ocean being lowered by...
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