Aspects of this topic are discussed in the following places at Britannica.
...a region of the liver cell called the rough endoplasmic reticulum, specific glutamic acid residues in the protein are changed by an enzyme-mediated reaction to form a modified glutamic acid known as γ-carboxyglutamic acid. This enzyme reaction, known as γ-carboxylation, requires vitamin K as a cofactor. γ-Carboxyglutamic acid is a unique amino acid that binds to calcium. In the...
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