Aspects of this topic are discussed in the following places at Britannica.
...the 5′ end of the mRNA, a modified guanine nucleotide, called a cap, is added. Noncoding nucleotide sequences called introns are excised from the RNA at this stage in a process called intron splicing. Molecular complexes called spliceosomes, which are composed of proteins and RNA, have RNA sequences that are complementary to the junction between introns and adjacent coding regions called...
in heredity: Mechanisms of mutation )...or it occurs at an inappropriate time because of alterations somewhere in the regulatory region. Fourth, mutations within introns that affect the specific nucleotide sequences that direct intron splicing may result in an mRNA that still contains an intron. When translated, this extra RNA will almost certainly be meaningless at the protein level, and its extra length will lead to a...
in heredity: Regulation of gene expression )Following the transcription of DNA into RNA, a process of editing and splicing takes place in which noncoding nucleotide sequences called introns are excised from the primary transcript, resulting in functional mRNA. For most genes this is a routine step in the production of mRNA, but in some genes there are alternative ways to splice the primary transcript, resulting in different mRNAs, which...
Link to this article and share the full text with the readers of your Web site or blog-post.
If you think a reference to this article on "gene splicing" will enhance your Web site,
blog-post, or any other web-content, then feel free to link to this article,
and your readers will gain full access to the full article, even if they do not subscribe to our service.
You may want to use the HTML code fragment provided below.
We welcome your comments. Any revisions or updates suggested for this article will be reviewed by our editorial staff. Contact us here.
Regular users of Britannica may notice that this comments feature is less robust than in the past. This is only temporary, while we make the transition to a dramatically new and richer site. The functionality of the system will be restored soon.